IMPlicating Mesenchymal Imp1 in Colitis-Associated Cancer.

نویسندگان

  • Ekaterina K Koltsova
  • Sergei I Grivennikov
چکیده

Chronic inflammation and associated pathways are significant facilitators of many disease states, including malignancies. In the context of cancer, fibroblasts can actively regulate both inflammation and carcinogenesis. In this issue, Hamilton and colleagues describe a fibroblast-specific role of the RNA binding protein Imp1 in suppression of intestinal inflammatory responses and development of colitis-associated cancer.

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عنوان ژورنال:
  • Molecular cancer research : MCR

دوره 13 11  شماره 

صفحات  -

تاریخ انتشار 2015